After the battle with the Mythos Cyborgs, Ivan warns the others of a Devil. Devilman too senses his enemy. The ultimate encounter is about to unfold.

Dr. Gilmore notices animal cells mutating into human cells on Joe’s wounds. Humankind’s worst enemy - humans? Joe and Akira’s fates are yet unknown.

Akira’s search for the abducted Miki Makimura leads to Devilman coming face to face with cybernetic demons generated through a horrifying ritual.